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CD40 antibodies

antibody cd40 from BioXCell

In immunology, the CD40 T-Cell Co-Receptor (CD stands for cluster of differentiation) is a protein complex and is composed of four distinct chains. Bio X Cell offers a variety of monoclonal antibodies, as well as recombinant proteins and isotype controls.

m CD40L
Product: MR-1
Cat. #: BE0017-1
Antigen: mur. CD40L/mur. CD154
Isotype: Hamster IgG
Recommended Isotype Control: Polyclonal Hamster IgG
Production Method: Stirred tank fermentation
Medium: Hybridoma-SFM + 1% FCS + Gln +Gluc + P/S
Purification Method: Protein G
Endotoxin: <2.00 EU/mg (LAL)
Purity: >95% (by SDS-PAGE)
Sterile: 0.2 micron filtered
Formulated in: PBS, pH 7.2
Applications: Flow cytometric analysis, inhibition of CD154 binding to CD40 and activation of B cells.
Storage: This product is stable for several weeks at 4 C as an undiluted liquid. For extended storage aliquot contents and freeze at -20 C or lower. Avoid cycles of freezing and thawing.

To view the complete catalog of all BioXCell product visit: http://www.bxcell.com/catalog

Antibody CTLA-4

Antibodies from BioXCell
CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor ctla-4 antibody (CD152). The both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation; the both molecules can also substitute for each other in this process. The question what are the differences in CD80 and CD86 competency has not been fully elucidated yet; there are still conflicts in results about their respective roles in initiation or sustaining of the T cell immune response.

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Last Modified: 2017-08-12 01:15:01